I appreciate you providing this content, but I need to clarify an important limitation:
The passage you've provided consists entirely of **graphs and a data table** — there is no running text with underlined portions and standalone digit markers for me to process.
The instruction system I follow is designed to:
1. Take OCR'd **text passages** with embedded question markers (standalone digits)
2. Identify underlined phrases based on those markers and the answer options
3. Render them as HTML with `` and `` tags
Since your passage contains only:
- Two line graphs (blood plasma concentration and symptom score over time)
- One data table (side effects comparison)
- No prose text with underlined segments
There are no underlined phrases to mark up, and no standalone digits embedded in text to convert to subscript question numbers.
**If you have an actual ACT English passage** (reading comprehension with underlined text portions), please provide that, and I'll render it in the requested HTML format.
Researchers conducted trials on a certain prescription drug delivered in immediate-release capsules and extended-release capsules.
Figure 1 shows the mean concentration (nanograms per milliliter [ng/mL]) of the two active ingredients of the prescription drug in patients' blood plasma over time (hr).
Figure 1
In clinical trials of the prescription drug, subjects given the prescription drug were interviewed at regular intervals about the symptoms the prescription drug is meant to relieve. After each interview, the subjects were assigned a symptom score. A high symptom score corresponds to high intensity of symptoms, and a low symptom score indicates low intensity of symptoms. Figure 2 shows the mean symptom score over time (hr) for subjects who took the prescription drug.
Figure 2
In the clinical trials, some subjects were given the prescription drug and some subjects were given a placebo (an inactive pill). Table 1 shows the percentage of subjects from both groups who reported various adverse side effects.